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Although traditionally regarded as environmental phenomena, bacterial biofilms are increasingly considered to play a role in many human infections. Detection of lung adenocarcinoma with ROS1 rearrangement by IHC, FISH, and RT-PCR and analysis of its clinicopathologic features. Patients with PPROM who are managed with AC have significantly less CNM than NAC patients.

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Coexistent membranous nephropathy and ANCA-positive crescentic glomerulonephritis in association with penicillamine. The main objective of this study was to investigate the relation between these skills.

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We searched the Cochrane Stroke Group Trials Register (last searched 3 October 2009). The specimens were then treated as follows: no treatment (control), bulb irrigation, brush-suction irrigation, or high-pressure pulsatile lavage (HPPL).

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During an ultrastructural analysis of morphogenesis of the colleterial gland of the silk moth Hyalophora cecropia, we found the first example of paired flagella associated with an insect secretory cell. We measured proliferation of cell lines expressing wild-type or F104S c-Mpl in response to thrombopoietin receptor agonists targeting the extracellular (m-AMP4) or transmembrane (LGD-4665) domains of the receptor by 1-methyltetrazole-5-thiol assay. Small bowel biopsy for malabsorption: comparison of the diagnostic adequacy of endoscopic forceps and capsule biopsy specimens.

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Other rare forms of demyelinating peripheral neuropathies map to chromosome 8q, 10q and 11q. Biological properties of hCG after removal of terminal sialic acid and galactose residues. For deficiency of uridine monophosphate synthase and interdigital hyperplasia, DFA plots showed higher densities of additive and dominance relationships among affected animals. In some experiments the suppression of seizure activity was preceded by a transient enhancement. The study was employed for the discussion of the scopes of the applied second-order chemometric tools, demonstrating the superiority of MCR-ALS to successfully resolve this complex system.

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Patients with unrecognized fractures of the cervical spine associated with head injuries run the risk of developing spinal cord compression and paralysis while undergoing treatment. To investigate whether MTs play a role in longevity determination in mammals, we measured the lifespans of wild-type (WT) and MT-1 and -2 gene knockout (MTKO) mice in a 129/Sv genetic background. To explore auditory outcomes following cochlear implantation (CI) in patients with vestibular schwannoma (VS) in the only hearing ear.

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The identities of 16 PIs, seven known scission products and five probable PI degradants were confirmed, most showing signs of set-off. Topical corticosteroids potentiate mucin secretion in the normal nose. There remains a group of patients with serious coexisting disease in whom careful consideration must be given concerning the risk of operation.

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The concentration of 4-en VPA, the presumed major factor in VPA-induced hepatotoxicity, was markedly increased, without liver dysfunction or hyperammonemia. Multilevel modeling was performed to determine which electromyographic blink reflex parameter showed the best correlation with subjective pain ratings.

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To investigate the antitumor effect of calcium phosphate cement incorporated with doxorubicin microspheres. Congenital asplenia with bilateral right-sidedness and normally related great arteries. Morphogenesis and clinicopathologic characteristics of recurrent carotid disease.

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It is estimated that if there were no lung cancer (the commonest type of cancer in both morbidity and mortality statistics in males in Finland) the annual deaths saved would yield 5,900 working years (both sexes combined). There is a high risk of drug-related problems in nursing homes due to polypharmacy, multi-morbidity and age-related changes. Existing posture prediction and motion simulation models generally lack the capability of simulating human obstruction avoidance during target reach. The purpose of this study was to evaluate the anti-MDR effects of SM and the associated mechanisms in MDR K562/A02 cells. For each individual tooth, the correlation between contraction gap width and shear bond strength was insignificant.

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Tumor suppressor U19/EAF2 regulates thrombospondin-1 expression via p53. Prenatal exposure to methamphetamine has been linked to intrauterine growth retardation and variety of withdrawal symptoms.

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The aim of the present study was to validate the application of HER2 testing with CNB specimens from primary breast cancers in terms of interobserver reproducibility and comparison with surgically resected specimens. Local production of inflammatory mediators during childhood parainfluenza virus infection.

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Tuberculosis mortality trends in Delhi after implementation of RNTCP. The enzymatic membranes were exposed to very low mechanical stresses and showed a very good catalytic performance and durability.

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Switch from actin alpha1 to alpha2 expression and upregulation of biomarkers for pressure overload and cardiac hypertrophy in taurine-deficient mouse heart. The purpose of this study was to obtain more information on the nature of the macromolecule to which Pseudomonas aeruginosa adheres. According to this scenario, the SRP executes its essential function on the membrane at a later stage of the targeting pathway. Retrospective collection of clinical charts of all the patients admitted for renal disorders following ICI in the University Hospital of Toulouse (France).

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The percentage of cells in S-phase is highest in frontonasal mass cultures. All three major steps in non-oxidative glucose processing--glucose transport, phosphorylation and glycogen synthesis--are found to be reduced in response to insulin in insulin-resistant type 2 diabetic subjects compared with controls. Congenitally athymic nude mice and their hirsute littermates with thymuses were infected with a normally avirulent cyst-producing strain of Toxoplasma gondii. Significant clinical improvement was observed in laser-irradiated acne scars compared with the untreated (control) scars after one or two 585 nm pulsed-dye laser treatments.

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The aim of the study was to uncover mechanisms of central compensation of vestibular function at brainstem, cerebellar, and cortical levels in patients with acute unilateral midbrain infarctions presenting with an acute vestibular tone imbalance. Two patients were resection the right heart and inferior vena cava tumor in the cardiopulmonary bypass, 3 months later were resection gynecologic uterine, double-accessories and broad ligament and were not treated with hormone. Membranes were apparently negatively stained and the ultrastructure of mitochondria, rough endoplasmic reticulum and Golgi apparatus was clearly discernible. Many models of smooth muscle ischemia have been developed to explain organ insufficiency or failure.

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Gelling properties of apohemoglobin S alone and in mixtures with hemoglobin S. He noticed improvement whenever he stopped using these materials and intense itching and worsening when he began reusing them. This purification is based on a C-terminal 6xHis-tag, which enables functional expression of the enzyme in E. Early predictors of traumatic glaucoma after closed globe injury: trabecular pigmentation, widened angle recess, and higher baseline intraocular pressure. Both modern neuroscience and clinical psychology taken as separate fields have failed to reveal the explanatory mechanisms underlying mental disorders.

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Metagenomic analysis of colonic mucosa-associated microbes has been complicated by technical challenges that disrupt or alter community structure and function. The extent to which pain should be alleviated and animal factors, such as breed, behavior, and clinical circumstances, accounted for much of the discordance among survey groups. We present a theoretical analysis on the ability of DBNs without hidden variables to learn from proteomic time series data.

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This observation, combined with the study of several point mutations, allows us to propose that the link made by the C-terminal arm of M547 between its N and C-terminal domains is essential to sustain an active enzyme conformation. The paramorphous action was manifested by beta-ionone in the presence of sunflower oil.

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Bilirubin secretion and conjujation in the Crigler-Najjar syndrome type II. Regulation of the lemon-fruit V-ATPase by variable stoichiometry and organic acids. The proposed registration framework and algorithm were evaluated on 15 real prostate cancer patients. The pathophysiologic mechanism is thought to be paresis of the posterior cricoarytenoid muscles secondary to ulceration and infection over the posterior lamina of the cricoid. In the current study, we show that delta 9-THC produces a marked inhibition of inducible nitric oxide synthase (iNOS) transcription and nitric oxide production by the macrophage line RAW 264.7 in response to lipopolysaccharide (LPS).

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Bioanalytical LC/MS study of potential bacterial transglycosylation inhibitors. Measurement of greenhouse gas emissions from agricultural sites using open-path optical remote sensing method. Etiology of the epidemic outbreak of community-acquired pneumonia in children in St.

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Interventions to provide performance feedback and training to the healthcare team, increase patient awareness and participation in the medication reconciliation process were implemented. In this study, it was examined whether similar lesions would occur in mother rats which were given AKW from day zero of gestation to day 20 of lactation.

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Future directions of research are discussed and include the need to understand coping as a process, identification of coping in relation to adaptive outcomes, and considerations of more complex mediational and moderational processes in the study of coping with CSA. The traditional differential set consists of potato lines with 11 late blight resistance specificities, referred to as R1 to R11. Partial resection of the hepatic segments IV-V provides excellent exposure of the hilar plate.

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Comparison of pancreatic digestive enzyme secretion induced by volatile fatty acids in mice, Japanese field voles and goats. A semiquantitative analysis of the protein expression was also performed. Unfortunately, limited evidence exists to guide clinicians in selecting the ideal drainage intervention for a specific patient because of the broad variation that exists in the intrapleural extent of infection, presence of locules, comorbid features, respiratory status, and virulence of the underlying pathogen. Pathological studies on nephrotoxic serum nephritis accelerated with rabbit gamma-globulin in mice.

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The method allows the immediate and rapid imaging of two-dimensional gels at the end of electrophoresis with no further processing. Legislation (PL 94-142) has made it mandatory for complete services to be provided to exceptional children from birth to age 21. In yeast, approximately 31 autophagy-related (Atg) proteins have been identified.

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Overexpression of IbpB enhances production of soluble active Streptomyces olivaceovirdis XynB in Escherichia coli. The widespread use of antiretroviral agents and the growing occurrence of HIV-1 strains resistant to these drugs have given rise to serious concerns regarding the transmission of resistant viruses to newly infected persons, which may reduce the efficacy of a first-line antiretroviral therapy. Replacement of codons in the green fluorescent protein (gfp) gene with those frequently used in PV late genes did not alter gfp transcription in Cos-1 cells but almost abolished translation, supporting the hypothesis that the observed differences in efficiency of translation of modified and unmodified PV capsid genes were related to codon usage rather than mRNA structure. These results indicate that although IL-10 plays a role in limiting the Th1 response during the acute infection phase, other immunomodulatory factors are responsible for limiting the Th1 response during the chronic phase.

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Acute altitude-induced hypoxia suppresses plasma glucose and leptin in healthy humans. HER2 mutations in Chinese patients with non-small cell lung cancer. By means of competition experiments, at least four epitope regions were found. Furthermore, exposure to hydrogen peroxide led to a decrease in Cdc42GAP activity in an in vitro assay.

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Despite an increase in the variety of anti-retroviral agents in the market, there remains a need for novel agents to treat HIV 1 infected individuals, in order to overcome existing problems with adherence, toxicities, drug interactions and viral resistance. Taken together, our findings identify a functional role for SOX genes in SCLC, particularly for SOX4 and several novel targets defined in this study. Time-dependent botulinum neurotoxin serotype A metalloprotease inhibitors. Due to its direct derivation from observed splice site selection, SP has an advantage over other computational approaches for predicting alternative splicing. As expected, transient shifts frequently occur with recreational use.

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Kinetic parameters of 5 alpha-reductase activity in stroma and epithelium of normal, hyperplastic, and carcinomatous human prostates. The NDI is a reliable evaluation instrument for disability but there is no published Turkish version. In this paper, we investigate deviations from MM law and their effects on the dynamical behavior of the enzymatic network. Internally, filaments which derived from capsules around the cells extended radially from a population of long rod-shaped bacteria.

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Axonal neuropathy with unusual clinical course in young Snowshoe cats. In the present study, upregulation of a 240 kDa protein was detected in C. The pathological examination showed fibromatosis of vulvar and thigh masses and fibroadenoma of breast lump. The genetic variation of CYP19A1 was associated with circulating estrogen levels in Chinese elderly men. In the absence of p47phox, sinus nodal cells were highly resistance to Ang II-induced apoptosis, suggesting that oxidized-CaMKII contributed to sinus nodal cell death.

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The results of this study demonstrated the efficacy of deployment of bare-metal stents and coronary artery bypass grafting surgery for subsets of patients. The nature of these impairments early in the course of illness and the impact of antipsychotic drug treatment on these deficits are not well understood. The duration of functional availability of stimulus information for stimuli at the five levels of redundancy was determined in a backward masking paradigm. We examine the use of and physical activity outcomes associated with rural and urban parks.

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The Staphylococcus aureus surface protein G (SasG) is an important mediator of biofilm formation in virulent S. To assess the benefits and drawbacks of intraosseous infusion (IOI) for emergency therapy in children. Increased survival with hypotensive resuscitation in a rabbit model of uncontrolled hemorrhagic shock in pregnancy. One of the AOTFs was used as a dispersive element coupled to external imaging optics. This review will offer a deeper insight into this field, focusing on the properties of arginine, glutamine, antioxidants, and omega-3 fatty acids as well as the level of blood glycemia which should be maintained in critically ill patients.

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In emergencies involving the descending colon one-stage surgery may be performed without colonic preparation as safely as elective surgery in selected patients considered suitable for segmental resection of the descending colon and primary anastomosis. Responses in vitro of lymphocytes from patients with cervical dystonia and/or other movement disorders treated with BoNT/A or BoNT/B. Partial characterization of mucoran: the glucuronomannan component. In summary, our data demonstrate that BAF60a directly interacts with the coactivator groove in the AR ligand-binding domain via its FxxFF motif, thereby selectively activating specific AR-driven promoters. The TNF-alpha-induced activation of JNK1 is augmented in Miz1-deficient mouse embryonic fibroblasts (Miz1(-/-) MEFs), but the augmentation is abrogated by reintroduction of Miz1 or its transcription-deficient mutant.

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This staining pattern was not correlated with the staining pattern for macrophages. Magnetic resonance angiography in children: technique, indications, and imaging findings. We performed a systematic analysis to define the spectrum of anesthetic-related complications in patients with muscular dystrophy, with an emphasis on malignant hyperthermia susceptibility. Arterial switch operation: myocardial ischemia reversed by internal mammary artery graft.

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Absolute low-energy experimental cross sections for (e,2e) processes on helium. Endothelin-1 acts in cerebral arteries from the adventitial but not from the luminal side. In addition, no reported study has compared outcomes between the suture-bridge and double-row techniques. Actinic keratosis: precancer, squamous cell carcinoma, or marker of field cancerization? Mammary carcinoma with argyrophilic cells: an immunohistochemical and ultrastructural study.

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Cardiac Ca channel currents at the level of single cells and single channels. Stem cell technology for basic science and clinical applications.

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Three members from two generations of the same family, with familial amyloidosis, were screened for mutations in the GSN gene. Corrections to finite-size-scaling laws and convergence of transfer-matrix methods. Archaeal diversity in the haloalkaline Lake Elmenteita in Kenya.

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This down-regulation allows infected cells to evade recognition by cytotoxic T cells but leaves them susceptible to NK cells, which lyse cells that lack class I molecules. Impact of severe acute respiratory syndrome on patient access to palliative radiation therapy. These data suggest that the SF could be acting by either indirectly restricting IL-2 availability to proliferating CTLs by limiting adherent cell interleukin 1 (IL-1) secretion or, alternatively, SF acting directly on the IL-2-producing T cells. However, newer triazoles, echinocandins, and lipid-based formulations of amphotericin B are now approved for use in humans. MAC-321 is a novel taxane that has demonstrated exceptional activity in human xenograft models when administered intravenously and orally.