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All of the nucleotide could be polymerized during the course of the reaction. But, the expression of p21(Waf1) was increased, while p27(Kip1) and p53 were not detected in hydroxyurea treated rat hepatoma cells. Peak expiratory flow rate (PEFR), forced vital capacity (FVC), and forced expiratory volume in 1 second (FEV1 ) were measured before and after each treatment.

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Regarding appendectomy, comparison with standard laparoscopy, benefits and drawbacks of this novel technique remain to be evaluated. Yet, most of the evidence for the central effects of sex steroids relies on non-human studies, as several challenges have limited our understanding of these effects in humans: the lack of systematic assessment of the human sex steroid metabolome, the different developmental trajectories of specific sex steroids, the impact of genetic variation and epigenetic changes, and the plethora of interactions between sex steroids, sex chromosomes, neurotransmitters, and other hormonal systems. The defect is expressed in vitro by a depressed stimulation of pyruvate dehydrogenase catalytic activity by exogenous phosphoprotein phosphatase, and in vivo by a lack of response to muscle work, in comparison with healthy controls. The non-SP cells induced by macrophage-like cells showed more aggressive characters, which increased cell migration compared with the control cells and showed some fraction of SP phenotype.

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Compared to healthy epidermis, wound-edge keratinocytes from Dicer-ablated skin epidermis revealed elevated p21(Waf1/Cip1) expression. Quantitative evaluation of the brain electrical activity of patients suffering from chronic obstructive bronchopneumonopathy (COBP). A total of 5,698 men and 6,533 women, aged 35 to 69 at baseline in 1992, participated in the Takayama Study, a population-based prospective cohort study. Questions instead of being quiet--what doctors can do in cases of domestic violence

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Reverse transcription activity of OS-AF is stimulated only upon its exposure to ovalbumin and not to insulin while the reverse is true for the activity associated with IS-AF. Expression of OsCSLD4 fluorescently tagged at the C- or N-terminus in rice protoplast cells or Nicotiana benthamiana leaves showed that the protein is located in the endoplasmic reticulum or Golgi vesicles. Disclosure and reproduction of a fistula tract in the routine impression procedure by use of silicone rubber: report of case. Endocrine influences on the net extrarenal fluxes of sodium and potassium in the European eel (Anguilla anguilla L.). Effect of osmotic shifts in cerebrospinal fluid on lymph flow and lymph formation

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Oral melanomas vary in color and morphology and resemble myriad other reactive, benign, or malignant conditions. However, the level of 3beta-hydroxysteroid dehydrogenase type-I mRNA was not changed. Overall, there was no clinically significant difference between the periodontal-type measurements for HA-coated and non-HA-coated implants followed for a period from 3 through 36 months. Furthermore, we revealed that the PKC translocation requires neither the kinase activity of PKC nor its association with cytoskeletal proteins such as F-actin.

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Thirty-seven days after injection all rats were killed and ganglioside fractions were isolated from neocortex, hippocampus, brain stem, cerebellum and residual cerebral tissue of each one brain. Corticosterone-induced responses in rat brain RNA are also evoked in hippocampus by acute vibratory stress. By means of a micro-dilution technique (10(5) cfu/cup) 30 strains of Pseudomonas spp.

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TNF (tumour necrosis factor alpha) induces tolerance towards itself in experimental liver injury. The Segond fracture is considered highly suggestive of an anterior cruciate ligament (ACL) tear in the adult population. Postmenopausal women with early breast cancer patients took anastrozole 1 mg per day. Identification and Characterization of Wor4, a New Transcriptional Regulator of White-Opaque Switching.

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Their limitations include multiple food and drug interactions and need for frequent monitoring and dose adjustments. We previously showed that a plasmid bearing a mammalian replication initiation region could efficiently generate DMs and HSRs after transfection into human tumor cell lines. These and public health education campaigns set the stage for building motivation and confidence to stop smoking and reinforce the social value of non-smoking. The external muscle coat of the upper half of the esophagus in both species had several collagen coated bundles of striated muscle fibres around the circumference. Zygotic induction of mutants in cistron O resulted in a 5-fold depression of the linkage, while induction of mutants in cistron P and in the x region resulted in complete restoration of the linkage.

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The results are in favour of the nosological distinctiveness of mycosis fungoides within the lymphoma group. The mossy fiber terminals were not distributed equally over the cortex but showed a preference for the proximal parts of the individual lobules. Neuropathologic findings in the central areas on MRI demonstrated only the chronic and resolving grades, but active inflammatory abnormalities were present not only at the margins of the lesions, but also in areas of subtle signal abnormality on MRI. Anaphylaxis is of increasing prevalence and concern in Western communities.

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The prognostic value of vascular diameter measurements on routine chest computed tomography in patients not referred for cardiovascular indications. The fluorescein groups at both sites exist in an environment of reduced polarity as shown by a shift in excitation and emission maxima and a shift in the pKa of the fluorescein groups.

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Technetium bone scanning as an aid in the diagnosis of atypical acute osteomyelitis in children. Our preliminary results point at a training-induced reduction of bradykinesia. Reliability of the results of the ultrasonic hemodynamic recording (Doppler effect) in the diagnosis of cerebral ishemic ischemia of carotid origin

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Premedication of patients with cardiovascular pathology in minor stomatological operations Oral acute toxicity study was carried out by administering single geometric increasing doses (2 to 16 g/kg body weight) of plant extract to Swiss albino mice. Interpretation of currents recorded from single ion channels in cellular membranes or lipid bilayers is complicated by the necessarily limited time resolution of the recording and detection systems. The system was designed as a screening technique for assessing the irritancy of air pollutants. With f/l optics, this system is therefore capable of producing a focused intensity of 6.4 x 10(19) W/cm(2).

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The gene 5 and gene 8 messages decay with half-lives of approximately 2.5 and 5 min, respectively. Utility constraints limit the amount of generalization and are specified by data owners (e.g., the healthcare institution that performs anonymization). Diagnostic importance of jejunoperfusion in disorders of intestinal digestion and absorption Clinical efficacy of open reduction and semirigid internal fixation in management of displaced pediatric mandibular fractures: a series of 10 cases and surgical guidelines. Plaque, gingival bleeding and calculus formation after supragingival scaling with and without polishing: a randomised clinical trial.

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Juvenile hormone III induced frontalin biosynthesis in males and trans-verbenol biosynthesis in females, as well as affected the expression of many proteins and transcripts in sex- and tissue-specific ways. We tested ozone effects and investigated the potential of confounding due to changes in nutrient management. Chewing gum containing nicotine produced rises in plasma nicotine concentration similar to those observed after smoking tobacco cigarettes and was associated with a significant reduction in the incidence of fetal breathing movements. The results of this study, using real-time RT-PCR, support the proposal that c-fos mRNA can be used as a specific biomarker of excitotoxicity and moreover encourage further studies to employ this highly sensitive, quantifiable and reproducible technique in a high throughput screen, with minimal use of animals for primary culture set-up.

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Quadrivalent pairing is evident between the pairs of synaptonemal complex segments in the tetraploid nuclei. Radiation mortality in the Chinese hamster, Cricetulus griseus, in relation to age. The aim of the present study was to explore clinical and laboratory parameters that are associated with HCPR and HAPR as measured with different platelet function tests. The use of prostaglandin E1 in an infant with interruption of the aortic arch.

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Exercise resulted in activation of p38 MAPK and movement of PGC-1alpha into the nucleus. The use of lower procainamide doses and careful anticipatory monitoring of serum concentrations of procainamide and N-acetylprocainamide are essential in this high-risk group. The divergence of the growth time close to the onset of instability is also studied in detail. In five cases, a simplified anterior tarsal resection corrected complicated upper eyelid blepharoptosis and contour abnormalities.

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A brief review of the existing literature on this rare entity is also presented. The dual substituent parameter approach provides an excellent correlation when a combination of polar and resonance substituent constants is employed. She had a 3-year history of right-eye proptosis, bilateral nasal masses, and epistaxis. Since complications of BMT such as graft-versus-host reaction or severe infections are less frequent in children, relapses remain the main problem after BMT in childhood leukaemia.

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The effects of microcystins on the transcription of cytoskeletal genes may explain some of the morphological and pathological changes observed in these organs and provide new information on the hepatotoxicity of these compounds. Histological preparations with normal epithelium, dysplasia, carcinoma in situ and squamous invasive carcinoma of human cervix were studied by immunofluorescence using human sera containing antibodies against basement membrane material, against intercellular substance of squamous epithelium (ISSE) and against reticulin. Less than 100 pg/well of single-stranded DNA could be detected, and the detection was linear over a DNA concentration ranging from 0.34 to 34 ng/ml. Salvage oesophageal reconstruction that withstood the test of time.

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To determine the critical thermal dosimetry and relative efficacy for RF ablation combined with external beam radiation (XRT) or liposomal doxorubicin (LD), in an animal tumor model. By synthesizing several structurally related brain-gut-skin triangle peptides, a number of advantageous features of the thioanisole-mediated deprotecting procedure were demonstrated. The changes of lipid metabolism in advanced renal cell carcinoma patients treated with everolimus: a new pharmacodynamic marker? Ant-associated (myrmecophilous) aphid species disperse less readily than nonmyrmecophilous species. The strongest predictor of brain damage associated with substance dependence in this sample was dose (particularly quantity and duration of peak dose).

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