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Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1alpha. Under such conditions, the specimens produced stable trans-gap action potentials of relatively high amplitude.

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CXCL10 expression and prognostic significance in stage II and III colorectal cancer. The results suggest that cholinergic mechanisms have little influence on the feedback regulation. Therefore preoperative diagnosis of musculoskeletal hydatid disease is sometimes difficult clinically and radiologically.

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Effect of cholesterol on the membrane interaction of Modelin-5 isoforms. Acute thermal stressors and synthesis of antibodies in chickens.

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Identification of tyrosine 972 as a novel site of Jak2 tyrosine kinase phosphorylation and its role in Jak2 activation. We tabulated the number of studies by publication year and summarized methodological detail. A combined approach involving detailed morphological examination and sequencing of two independent DNA loci was used for their analysis. We studied occurrence, disease course, and prognosis of community-acquired bacterial meningitis in HIV-infected adults in the Netherlands. Multidetector computed-tomography (MDCT) scanners provide large high-resolution three-dimensional (3-D) images of the chest.

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There has been significant progress in the understanding of the pathophysiologic basis of common haematological problems like cytopenias, coagulopathies and thrombophilic disorders in the background of liver disease. Vitamin E is composed of two structurally similar compounds: tocopherols (TPs) and tocotrienols (T3).

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Cardiopulmonary interactions apparent with common complex heart and lung diseases evolve concurrently from early adulthood forward. A secondary goal was to evaluate the pharmacological profile of ABC294640, when given in combination with methotrexate. This study evaluated the effect of corticotropin-releasing hormone (CRH) on locomotor activity, habitat choice, and social behavior in juvenile spring chinook salmon (Oncorhynchus tshawytscha). VLDL1- and VLDL2-TG turnover were measured during a 4 h basal period and a 3.5 h hyperinsulinaemic clamp period using a primed-constant infusion of ex vivo labelled VLDL1-TG and VLDL2-TG.

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The Chinese students had significantly higher scores than the Korean students on the professionalism and communication skills. Medetomidine alone did not give sufficient restraint to permit intravenous access. Stimulation of the motor branch of the pudendal nerve during erection elicited by cavernous nerve stimulation was responsible for an additional ICP increase, which reached suprasystolic values. Identification of key pathways and genes in psoriasis via gene microarray analysis. The absence of virulence defect of the sortase mutants could be a consequence of the membrane localization of the cwss proteins.

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The kdAkt mutant protein attenuated the constitutively active PI3K-induced overgrowth of the heart, and the caAkt mutant protein circumvented cardiac growth retardation induced by a kinase-deficient PI3K mutant protein. The rate of uptake of new medicines in the UK is slower than in many other OECD countries. The gene defective in beige is thought to be a homologue of the gene for the human disorder Chediak-Higashi syndrome.

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We recently demonstrated that conditioned medium (CM) from peritoneal macrophages or activated microglia triggers a predominantly apoptotic death in hippocampal neurons in culture. Therefore the helper function of MDCK cells must be distinguished from a community effect where the contribution of low tumorigenic cells not only provides an in vivo growth advantage to few highly tumorigenic cells but become themselves highly tumorigenic indicating that the community effect may require cell-cell specific cooperativity independent from an helper effect. In the absence of the inducer, transgenic seedlings remained sensitive to ethylene, but in its presence, a state of ethylene insensitivity was induced, resulting in the elongation of the hypocotyl and root in dark-grown seedlings in the presence of ethylene, a reduction or absence of an apical hook, and repression of ethylene-inducible E4 expression. These lesions were regarded as a duplicated inferior vena cava (IVC) and this was confirmed at retroperitoneal lymph node dissection. This approach compares outcomes in the United Kingdom before and after the introduction of BTC simvastatin, using outcomes in countries where the drug remained prescription only to control for possible confounders.

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These MRI-based biomarkers may have the potential to identify individuals at the highest risk of developing psychosis, and thus may promote informed clinical strategies aiming at preventing the full manifestation of the disease. We conclude that, to scale up this type of mixing, the kinetics of impurity removal need to be determined experimentally for the systems and equipment under consideration. Regulation of alpha 2-macroglobulin synthesis in primary cultures of rat hepatocytes by humoral factors

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Portal-hypertensive rats were allocated to one of the four groups: vehicle group (saline, 0.5 ml/12 h), octreotide group (30 microg/kg/12 h), DL-028 group (0.4 mg/kg/12 h), and octreotide (30 mg/kg/l2 h) plus DL-028 (0.4 mg/kg/12 h) group, with eight rats in each group. Fractionation of urinary glycosaminoglycans using ethanol, their purification and study

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Twenty percent of patients who experience spontaneous spinal CSF leaks have minor skeletal features of Marfan syndrome. Nursing care planning should incorporate interventions that aim to prevent or reduce RSS. Isothiocyanates also inhibit mitosis and stimulate apoptosis in human tumor cells, in vitro and in vivo. Interestingly, overexpression of AP-1 protein partially restored eNOS expression and endothelial cell proliferation.

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Regardless of the concentration of 25OHD in blood used to define vitamin D deficiency, hypovitaminosis D was common in these subjects. Colporrhaphy compared with mesh or graft-reinforced vaginal paravaginal repair for anterior vaginal wall prolapse: a randomized controlled trial. Adaptation to a visual pattern can alter the sensitivities of neuronal populations encoding the pattern. Reductions in microinvertebrate populations could have impacted higher organisms in the aquatic food chain such as striped bass and chinook salmon. Endothelin-1 (ET-1) is a potent vasoconstrictor that causes pulmonary vasculopathy.

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The cause of death and the possible relationship between the pulmonary vascular lesions and the DACA are discussed. gamma-Aminobutyric acid (GABA) is one of the major inhibitory neurotransmitters in the central nervous system. The compounds were obtained as yellow powders after sequential purification by chromatography on MCI Gel CHP20P, Fractogel HW-40 and ODS reversed phase chromatography.

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This retrospective analysis suggests that conditioning regimens intensified with IDA can achieve better outcomes than conditioning regimens with VP16 in patients preparing to undergo allo-SCT for high-risk acute leukemia. University of Maryland Exercise Science and Wellness Research Laboratories. Regulation of N-linked glycoprotein assembly in uteri by steroid hormones.

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The confounder-adjusted hazard was compared with mortality tables of the German population. These observations suggest that nanoparticles aggravate oxidative stress following hyperthermia leading to exacerbation of neurotoxicity through oxidative stress-related mechanisms, not reported earlier. Immediately starting an empiric antibiotic is important in treating pulmonary infections in heart transplant recipients. New developments and a call to action for home care on Capitol Hill.

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Using Random Forests (RF) algorithm in the training set, predictor genes for FOLFOX therapy were identified, which were applied to test samples and sensitivity, specificity, and out-of-bag classification accuracy were calculated. Cystic pancreatic lesions vary from benign to malignant entities and are increasingly detected on cross-sectional imaging.

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The poorer virological responses in children may increase the likelihood of emergence of resistance. Dutch doctors withhold and withdraw treatment in many elderly patients, study finds. To investigate the leukemia risk in a group of benzene exposed workers.

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Especially immunostaining requires laboratory procedures adapted to cytology samples. We describe 25 patients with computed tomographic evidence of peripheral pulmonary lesions (PPLs) who underwent bronchoscopy with endobronchial ultrasonography (EBUS) for localization. Scavenger receptor class B type I (SR-BI) is an essential receptor for hepatitis C virus (HCV) and a cell surface high-density-lipoprotein (HDL) receptor. By using MTT test, NBT reduction reaction and DNA agarose gel electrophoresis, changes in proliferation, differentiation and apoptosis were observed in K562, HL-60 and fresh leukemia cells after treated with 5-aza-CdR. Plagiarism, Cheating and Research Integrity: Case Studies from a Masters Program in Peru.

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Nafoxidine hydrochloride can provide additional palliation to patients who responded to previous endocrine ablation and had tumors containing an estrogen receptor. Early innate immunity responses in the gut are associated with the emergence of sensitization and atopic dermatitis later in childhood. Reversible and irreversible alterations of lysosomes in ischemic rat-liver. In human ovarian adenocarcinoma OVCAR3 cells sensitive to both IFN-alpha and IFN-gamma, only IFN regulatory factor 9 (IRF9)-RNA interference (RNAi) completely inhibited the antiproliferative activity of IFN-alpha among the intracellular JAK-STAT pathway factors. Production of cAMP by the Sertoli cells was markedly enhanced by follitropin, but not at all by insulin.

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A total of 49 protein sequences of alkaline proteases retrieved from GenBank representing different species of Aspergillus have been characterized for various physiochemical properties, homology search, multiple sequence alignment, motif, and super family search and phylogenetic tree construction. The aim of this study was to evaluate and describe the results of surveillance of HAIs in a III level NICU in Naples, Italy during 2006-2010. Follow-up consisted of 10 visits (96 weeks), electronic data collection (EDC) within 7 days of a visit and serious adverse events (SAEs) reported within 24 hours of site awareness. In the patients with liver cirrhosis, corresponding to the stage of gastric mucosa alterations, a considerable decrease of the delomorphus cell number was established as compared with the healthy subjects. Positional candidate gene approach and functional genomics strategy in atopy gene discovery.

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Upon immunization of mice, the bovine serum albumin-conjugated 14,000-molecular-weight fragment, the unconjugated 14,000-molecular-weight fragment, and the native glycoprotein all induced a similar neutralizing antibody response, albeit to a lesser extent than did the infectious, whole virus. Each of these three species is associated with a preferential organotropism: articulation for B.b. Frequency of abdominal aortic expansion after thoracic endovascular repair of type B aortic dissection.

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Chemical force microscopy (CFM) based on tapping mode Atomic force microscopy (AFM) utilized with topographic and phase-shift analyses was used to investigate the topography and surface chemical properties, respectively, of the long trichoid sensilla on the antennae of male Helicoverpa zea. The pectoralis minor pedicle flap is easy to dissect and reproducible, involving minor esthetic sequelae and no functional complications.

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Theory for the ultrafast structural response of optically excited small clusters: Time dependence of the ionization potential. beta-endorphin also decreased the binding of radiolabelled IL-2 or IL-2 receptor-positive human lymphocytes. The hypoxia-inducible factors (HIF-1a and HIF-2a) have been identified as key proteins that directly respond to hypoxic stress.

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Here, we examine the integrity of suppressive center-surround mechanisms in motion perception of schizophrenic patients. The allergic reaction led to the diagnosis of echinococcosis, which was confirmed by serological examination. The main advantages of SPECT/CT are represented by better attenuation correction, increased specificity, and accurate depiction of the localization of disease and of possible involvement of adjacent tissues.

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This study develops a simulation platform using computer models based on the computed tomography images of the femoral head to evaluate the degree to which transtrochanteric rotational osteotomy moves the region of osteonecrotic femoral head out of the weight-bearing area in stance and gait cycle conditions. A double isotopic, differential labeling technique followed by gel electrophoresis of extracts in the presence of sodium dodecyl sulfate revealed the presence of a polypeptide, or polypeptides, in human erythrocyte membranes, the reactivity of which to 1-fluoro-2,4-dinitrobenzene was significantly enhanced in the presence of D-glucose.

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Previously, we have for the first time reported enlargement of the pig kidney during long-term ciclosporin (CsA) treatment. Cellular differentiation was noted in the pharyngeal hypophysis in both rats. The selective one- and two-electron reduction of azo-pyridine and azo-1,8-naphthyridine with anionic CH3COO- by the Kolbe reaction has been established for the first time, and reaction mechanisms are presented. However, it is possible that in a few cases the control growth measured with preparation microscope is somewhat exaggerated due to inflammatory reactions induced by the grafts. Simultaneous sampling was performed to determine whether saliva could replace plasma in the monitoring of theophylline dosages.

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The intrathecal administration of metrizamide resulted in transient leakage of serum components into CSF and an accompanying transient meningitis. Detection of hypertrophic pulmonary osteoarthropathy of skeletal imaging with 99mTc-labeled diphosphonate. Evaluating radiation dose of 128-slice dual-source computed tomographic coronary angiography with different electrocardiogram pulsing models

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Evaluation of the phadebact and bactigen reagents for detection of Neisseria meningitidis in cerebrospinal fluid. The mycobacterial 65 kD heat-shock protein and autoimmune arthritis. These data suggest the possible involvement of GD3 and NG2 in pre/pro-tumorigenic events occurring in the complex microenvironment of the tissue surrounding GBM.

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Nineteen boys with stenosis of the external urethral meatus underwent urodynamic investigation. Radiation received by the ovaries during various x-ray examinations performed for diagnostic purposes. No difference was detected between the examined groups in transferrin (TRF) and alfa-1-antitrypsin (A1AT).

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All patients had intratumor cysts and these fluids with corresponding serum and cerebrospinal fluid were tested for their chemotactic ability. We identified 5 biomarkers associated with increased near-term risk of MI independently of established risk factors. We know of only one report on the migration of a gutta-percha point that had been used to fill a root canal into the ethmoid sinus. Studies comparing immediate OA versus diagnostic laparoscopy (followed by LA or OA if necessary) were separately identified. Improved potency assay for recombinant bovine somatotropin by high-performance size-exclusion chromatography.

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This report describes the use of a bovine pericardial patch to close the aortic outflow tract in a patient with a mechanical aortic valve and end-stage cardiomyopathy who required urgent left ventricular assist support. In children BMI and its centile correlate with ambulatory blood pressure levels stronger and more significant than other physical development factors. In a child with a hypothalamic glioma, elevated intracranial pressure and retrograde optic tract atrophy produced distinctive patterns of papilledema and disc pallor in each eye.

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It has also been suggested that where organophosphorus anticholinesterase compounds are handled continuously for many months in the year, for example, in crop spraying and in industry, P2S might be taken prophylactically. Whole blood was obtained from patients with metastatic HCC or NMLD. Selected overview of nongynecologic surgical intra-abdominal infections. Although factors associated with elevated left ventricular mass have been sought and studied extensively in elderly and in diseased subjects, few studies have examined the young and healthy.

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Although the final course seems satisfactory on the majority of cases, the possibility of a slow cirrhogenic transformation cannot be excluded in certain instances. Remarkably, the native gD expressed by rLaSota/gDFL virus was incorporated into the NDV virion 2.5-fold more efficiently than the native NDV proteins, whereas the chimeric gD was not detectably incorporated even though it was abundantly expressed on the infected cell surface.

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Colorectal cancer (CRC) is the third-leading cause of cancer death for both men and women in the USA. Human (H-MBP) was considerably less potent than Gp-MBP, and region 69-84 (H-S49S) of H-MBP did not induce hind leg paralysis or any histological signs of EAE. There was significant heterogeneity in the cytokeratins present in the different polyps. The purified MSHA was revealed as a globular form of protein under electron microscope. 2/14 patients died without change of the disease (NC) after 30 and 60 days respectively.

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The in vitro effects of alpha-difluoromethyl ornithine (DFMO) on the growth and the secretion of alpha-fetoprotein (AFP) and albumin in human hepatoma cell line PLC/PRF/5 were studied. The high rates of abstinence achieved in this trial suggest that promoting healthy sleep physiology in an inpatient setting may be important in the effective treatment of cocaine dependence. The ELISA assay of the sera also supported an increasing SHBG level along with age. A pilot study of the implementation of WHO surgical checklist in Finland: improvements in activities and communication.