Disulfiram continues to be prescribed as part of alcohol treatment programs and is being more widely studied for other drugs of abuse. Disulfiram toxicity associated with acute overdose, chronic therapy, and from Disulfiram—ethanol reactions continues to be reported worldwide. Most of the adverse effects are from case reports and case series which are difficult to interpret because of complications and comorbidities associated with alcohol use and alcoholism, the potential effects of polypharmacy, use of other drugs of abuse, and difficulty in relating specific adverse effects to Disulfiram, alcohol or a Disulfiram—ethanol reaction. Although serious and life-threatening effects associated with Disulfiram are rare, clinicians and toxicologists must remain vigilant in diagnosing and appropriately managing patients with Disulfiram associated toxicity.
Other names for this medication:
Disulfiram,
Antabuse,
Anticol,
Aversan,
Esperal,
Etabus,
Tenutex,
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