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In the northern hemisphere, interest is increasing in how species responded to changes in ice coverage and temperature during the last glaciation maximum (LGM, between 18000-21000 yr ago) with a common assumption that glacial refugia were located at the southern edge of a species range. YidC is involved in the biogenesis of anaerobic respiratory complexes in the inner membrane of Escherichia coli. In a fictitious example we assessed the impact of survival assumptions on the estimated costs per quality-adjusted life-year (QALY) gained, by using the survival functions of three previous cost-effectiveness analyses along with the two new survival functions.

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Distinct expression pattern of IFN-alpha and TNF-alpha in juvenile idiopathic arthritis synovial tissue. A DNA fragment (THR1) homologous to BRM2 was subcloned from pCR1 and the nucleotide sequence determined.

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Dexamethasone is a water-soluble steroid which is safe to be used in the third trimester, especially as a local treatment. Splenectomy done during hematologic remission to prevent relapse in patients with thrombotic thrombocytopenic purpura. With no available data, the sustainability of this care pathway has been questioned. That is, organelles containing newly synthesized membrane components move primarily anterogradely and organelles that contain transformed and degraded membrane components move retrogradely. Notch signaling: key role in intrauterine infection/inflammation, embryonic development, and white matter damage?

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Neurogenic responses in resistance vessels: roles of alpha 1- and alpha 2-adrenoceptors, transmitter reuptake, ouabain, and plasma factors. Coupling cell cycle exit, neuronal differentiation and migration in cortical neurogenesis. Between both phases, the reactivity of ConA and RCA showed almost no change. Toward the 25th Congress of the CPSU: let us raise the effectiveness of medical work and the quality of training of health personnel

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By introducing these hybrid genes into human squamous carcinoma CHU-2 and mouse macrophage BAM3 cells, the enhancer core element of the GPE3 was localized to the region from -98 to -79 in the promoter. Studies were carried out in the rat to detemine if hypothalamic lesions which caused polydipsia and polyuria had their effect mediated through an alteration of the ability of the neurohypophyseal system to release ADH. Synthesis and stability of a homologous series of triynol natural products and their analogues. The cross-reactivity of 3F8 with NCAM has been confirmed by cross-blocking studies with an anti-NCAM antiserum, and by direct immunoprecipitation and gel electrophoresis.

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Does parental report of insurance status agree with hospital administrative data for children presenting to the ED? The tumor spreads by local extension, to regional lymph nodes, or by distant metastasis. Comparison of the status of patients in the experimental and control groups during treatment demonstrated advantages of TcDMT in relation to improving the functional state of the CNS, memory, and attention, the autonomic nervous system, and the psychoemotional status of the patients (with decreases in the severity of anxiety and depression). Few studies exist involving patients with coagulopathies who undergo circumcision. The deletion mutant (yjr043cdelta) shows slow growth at low temperature (15 degrees C), while at 30 degrees C and 37 degrees C the growth rate of mutant cells is only moderately affected.

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Most inexpensive computer displays, and most grayscale image formats contain only 256 gray shades. Monozygosity is well established and in both cases the paraprotein was IgG kappa. Use of prognostic variables together with qualitative and quantitative results from clinical drug trials may aid the clinician and owner to plan and decide on optimal management of the myxomatous mitral valve disease dog. Our results show that the transmembrane helices of protein channels and transporters are significantly more loosely packed compared with helices in globular proteins. A significant decrease of fibrinogen was noted in patients with poor prognosis.

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Eighteen male, New Zealand white rabbits were anesthetized and spinal cord ischemia was induced by temporary occlusion of the descending thoracic aorta by a coronary artery balloon catheter, advanced through the femoral artery. This paper considers the conditions for obtaining an antireflection coating for two distinct wavelengths. With an increasing dual burden of disease in Sub Saharan Africa the associations between diseases and our understanding of them will become of increased public health importance. Genetic studies on natural resistance to Moloney lymphoma (YAC) isografts.

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Progressive Structural Brain Changes and NRG1 Gene Variants in First-Episode Nonaffective Psychosis. For the period 1997-2009, data on outpatient use of systemic quinolones aggregated at the level of the active substance were collected using the Anatomical Therapeutic Chemical (ATC)/defined daily dose (DDD) method (WHO, version 2011), and expressed in DDD and packages per 1000 inhabitants per day (DID and PID, respectively). 12 MW peak power from a two-crystal Yb:KYW chirped-pulse oscillator with cavity-dumping. Some fathers of mentally retarded children appear subject to a pattern of neurotic-like constriction. Our results show that MSI gastric carcinoma frequently shows activation of EGFR-MAPK and PI3K pathways.

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Glomerular filtration rate measurements were performed at baseline, 3 months posttransplantation, and yearly thereafter. The risks for embolization and continued expansion necessitate repair. Clear cell sarcoma originating in a paraspinous tendon: case report and literature review. In this study, we examined the mechanisms of photoinhibition of seminal root growth.

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D2 gastrectomy improves survival in gastric cancer, particularly in stage IIIA. Twenty-three patients received 3,000 MBq radioiodine following near-total thyroidectomy. The effects of intravenous infusion of the calcium antagonist, diltiazem (6, 30, and 150 mg/kg/hr) on cardiac and circulatory hemodynamics and on regional blood flow and cardiac output distribution to the major peripheral circulations were studied in conscious, normal Sprague-Dawley rats in the resting state. Cannabis use moderately increases the risk of psychotic symptoms in young people but has a much stronger effect in those with evidence of predisposition for psychosis.

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Computer-assisted interactive three-dimensional planning for neurosurgical procedures. Relatively little research has examined which types of victimization are most closely linked to suicide, which is necessary to develop targeted prevention interventions. Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation. On the other hand, anxiety is often believed to exacerbate pain in clinical situations, and anxiety reduction has been shown to attenuate the affective component of pain.

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Samples were collected in both plain (serum) tubes and plasma tubes for comparison. Pathological findings of the solid area was compatible with mucoepidermoid carcinoma of the thymus. Utilization of the iron of egg yolk for hemoglobin formation by the growing rat. This advantage can be exploited for wheelchair autonomous navigation.

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According to the present study, the two-steps/self-etch (Optibond XTR) adhesive system tested could be more effective on irradiated dentin compared to three-steps/etch-and-rinse adhesive system (Optibond FL). This close coupling suppresses transcriptional termination at an attenuator preceding the structural genes. Epidemiological investigations indicated that the disease was introduced into Japan approximately one month before detection. The projections of low threshold afferents from the oral cavity and the face to the cerebral cortex of cats anaesthetized with chloralose were investigated.

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Alterations in resting membrane properties during neural plate stages of development of the nervous system. Bacillus Calmette Geurin (BCG) skin immunization is an adjuvant therapy for malignant melanoma patients. Using electrospray mass spectrometry in native conditions, we found that Zn was bound to recombinant AdcAII. Over the last few years, groundbreaking scanning tunneling spectroscopy (STS) experiments have provided unprecedented new insight into the electronic structure of Kondo systems.

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The majority of cases only required a unipedicular injection, with bipedicular injections in 3 cases. Improved Hill determinant method for the solution of quantum anharmonic oscillators.

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However, studies to date have been inconclusive as they have not taken into account the influence of age. The specific cardiac defects detected in our cohort were variable, and studies with a larger number of patients are needed to establish which forms are most common. QTD measurement error is large compared with typical QTD values reported. The salivary cotinine concentration by sex, age, educational level, day of week of saliva collection, and exposure to SHS were always higher in hospitality workers than in the general population. Strain variation and geographic endemism in Streptococcus iniae.

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Nonoperative treatment of closed displaced midshaft clavicle fractures. The patterns and clinical relevance of contact allergen sensitization in a pediatric population with atopic dermatitis.

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The alkaline phosphatase activity of the slower zones is significantly less stable to heat than that of the zone characteristic of parenchymal cells. Basaloid adenomas of the mammary gland in beagle dogs administered investigational contraceptive steroids. Fatal air embolism during sigmoidoscopy performed under spinal anesthesia.

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Thus, exogenous Neu5Gc reaches lysosomes via pinocytic/endocytic pathways and is exported in free form into the cytosol, becoming available for activation and transfer to glycoconjugates. Twenty paraffin-embedded human tissue specimens, including normal, inflammatory, and neoplastic thyroid sections, were analyzed by immunohistochemical staining for expression of human COX-2. Dietary supplementation with alpha-amylase inhibitor wheat albumin to high-fat diet-induced insulin-resistant rats is associated with increased expression of genes related to fatty acid synthesis in adipose tissue. Roentgenologic and anatomical studies of the mandibular canal and its branches with special reference to differential diagnostic aspects The method was more sensitive than the ordinary ELISA as the final enzyme reaction was amplified through the use of the ABC system.

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The thickness of the left and right thyrohyoid muscles was measured in normal male and female adults ranging in age from 20 to 79 years by ultrasonography. Recent studies have shown the up-regulation of Toll-like receptors (TLRs) in patients with IgAN or IgAVN. The increase in MMP-9 levels was associated with a decline in the TH-2 type inflammation. The optimal blastomogenic 238Pu amount (92.5 kBq X kg-1) administered during the chronic period of the disease caused complex changes of atrophic, hyper- and neoplastic nature the lymphoid component of the thymus being primarily damaged.

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New and improved solutions, more cooperation between employees, and improved collaboration with patients and their families are some of the results. The anti-A2m(2) monoclonal antibody was shown to be specific for the corresponding allotype. To examine a possible effect of lithium on pHi and the relationship between pHi and WMHI, seven drug-free euthymic bipolar patients were examined, and T2-weighted MRI were examined in 14 previously reported bipolar patients. Significant improvements were also found for the TUG, DGI and MS Walking Scale between baseline and 3-month follow-up assessments. Of great influence on the results of measurements are preparation and registration (warm-up-time, amplification, closeness of pressure-system, unhurt catheters), factors relating to equipment and methods (air-bubbles in pressure-system, damping by filters, continuous infusion of the micro-catheter, level of zero-pressure), factors which occur during intravital measurement (pressure-drop along the arteria pulmonalis, influence of normal breathing, great intrapleural pressure changes, pressure damping in the catheter by thrombosis and external disturbances) and last not least positive and negative acceleration forces, which influence the diastolic and systolic pulmonary artery pressure.

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Computational protein design with side-chain conformational entropy. Scanning electron microscope observations of Amoeba proteus during phagocytosis. Structure and epitope specificity of human melanoma-associated oncofetal antigen gp87 analyzed with monoclonal antibodies. More than 400,000 workers annually receive a measurable radiation dose and may be at increased risk of radiation-induced leukaemia.

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When vomiting occurs early in the attack, treatment is best given by suppository, inhalation or intramuscular injection. We used human gastrointestinal cancer cell lines and examined how anticancer agents induced cell killing and how the chemosensitivity of these lines was determined. Effect of feed/inoculum ratio on anaerobic digestion of sonicated sludge. EAC3b incubated with sections of myelinated nerves pre-incubated with anti-CR1 antibody or with sections of unmyelinated nerves which contain functionally inactive CR1 were not degraded. A conductimetric method for the determination of sulphate and carboxyl groups in heparin and other mucopolysaccharides.

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The study included two designs, a quasi-experimental pre/post study with concurrent control group and a random sample of GPs within the intervention group. Table 3 summarizes the clinical effects of the newer therapeutic agents reviewed. Dynamics of the indicators of blood circulation in children with bronchial asthma treated by reflexotherapy Post hoc comparisons were made of IQ subtest scores and of language versus verbal IQ.

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It is suggested that in order to prevent stone recurrence, EHDP may be clinically applied not only to calcium phosphate stones but also to calcium oxalate stones and hypercalciuria mediated by an active form of vitamin D. The in-vitro activity of ceftazidime against clinically important pathogens. The mouse diaphragm, at stage ranging from embryonic day 18 (ED18) to postnatal week 10 (PW10), was observed by scanning electron microscopy, and the number of lymphatic stomata was counted on each observation day. Vimentin filaments support extension of tubulin-based microtentacles in detached breast tumor cells. Results revealed higher frontal midline theta activity for the manipulation of maintained stimulus material compared to pure retention of stimulus material.

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A shelf-stable loop-mediated isothermal amplification (LAMP) reagent for Burkholderia pseudomallei detection is described. Administration of articaine anesthesia may lead to superior profound pulpal anesthesia compared with lidocaine in adult patients. Significant correlations were found between concentrations of UV stabilizers and organic carbon content in sediments, implying adsorption of these compounds to organic matter.

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Wild-type islets were cultured with or without PL and examined for Foxm1 induction. Mitral regurgitation: clinical patterns, pathophysiology and natural history.

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Techniques of slurry preparation (liquid media, stabilizing agents, mass/volume ratio, particle size and slurry homogenization systems), the chemical modification, background correctors, calibration, precision and trueness of analysis were described in detail. Lidocaine jelly (2 ml) was instilled and lithotripsy was performed with a Swiss LithoClast . Neuronal substrates of motor learning in the velocity storage generated during optokinetic stimulation in the squirrel monkey.

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Recently, an origin from a remnant of the cervical sinus of His was proposed. Such techniques will make it possible to identify the structural defects that give rise to abnormal GABA receptor function and possibly to sleep, anxiety and seizure disorders. Intraoperative routine cholangiography in laparoscopic cholecystectomy