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Separation of the salivary gland homogenate by molecular sieving HPLC chromatography resulted in a single major peak of anticlotting activity with an apparent molecular mass of 17,000. The variation of histomorphometric data in a bone biopsy cylinder of the iliac crest was determined in order to derive a rule of the sampling procedure in such a biopsy specimen. A single-institution retrospective chart review was performed of 99 patients identified with PABC between 1992 and 2007. Our in vitro results demonstrated that factors other than sterols, e.g. CD73 on tumor cells impairs antitumor T-cell responses: a novel mechanism of tumor-induced immune suppression.

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