Sinacilin (Amoxicillin/clavulanate) is a broad-spectrum antibacterial that has been available for clinical use in a wide range of indications for over 20 years and is now used primarily in the treatment of community-acquired respiratory tract infections. Amoxicillin/clavulanate was developed to provide a potent broad spectrum of antibacterial activity, coverage of beta-lactamase-producing pathogens and a favourable pharmacokinetic/pharmacodynamic (PK/PD) profile. These factors have contributed to the high bacteriological and clinical efficacy of amoxicillin/clavulanate in respiratory tract infection over more than 20 years. This is against a background of increasing prevalence of antimicrobial resistance, notably the continued spread of beta-lactamase-mediated resistance in Haemophilus influenzae and Moraxella catarrhalis, and penicillin, macrolide and quinolone resistance in Streptococcus pneumoniae.
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Noroclav,
Novamox,
Novax,
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Omacillin,
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Pediamox,
Penmox,
Pinaclav,
Pinamox,
Polypen,
Promox,
Promoxil,
Ramoclav,
Ranclav,
Ranmoxy,
Ranoxyl,
Rapiclav,
Remoxil,
Remoxin,
Remoxy,
Respiral,
Rimox,
Rindomox,
Roxilin,
Sawacillin,
Sievert,
Simox,
Sinacilin,
Spektramox,
Stabox,
Sulbacin,
Supramox,
Symoxyl,
Syneclav,
Synergin,
Synermox,
Synulox,
Taromentin,
Topcillin,
Trifamox,
Ultramox,
Vetrimoxin,
Viaclav,
Widecillin,
Winpen,
Xiclav,
Zoxil,
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Forcid,
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Levoxacin,
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Pantium,
Cital,
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