Zocef axetil is an orally active prodrug of Zocef. After oral administration, Zocef axetil, as Zocef, is absorbed from the gastrointestinal tract and rapidly hydrolyzed by nonspecific esterases in the intestinal mucosa and blood to release Zocef into the blood stream. Conversion to Zocef, the microbiologically active form, occurs rapidly. The inherent properties of Zocef are unaltered after its administration as Zocef axetil. Zocef exerts its bactericidal effect by binding to an enzyme or enzymes referred to as penicillin-binding proteins (PBPs) involved in bacterial cell wall synthesis. This binding results in inhibition of bacterial cell wall synthesis and subsequent cell death. Specifically, Zocef shows high affinity for PBP 3, a primary target for Zocef in gram-negative organisms such as E. coli.
Other names for this medication:
Cefuroxime,
Ceftum,
Zocef,
Cefakind,
Supacef,
Altacef,
Oratil,
Stafcure,
Pulmocef,
Zefu,
Ceftin,
Kefurox,
Zinacef,
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Trimol,
Renacidin,
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